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Знание

Material Safety Data Sheet: Ellagic Acid

Identification

Product Name: Ellagic Acid
Chemical Formula: C14H6O8
CAS Number: 476-66-4
Relevant Identified Uses: Laboratory research, dietary supplements, cosmetics, antioxidant applications
Manufacturer Information: Contact listed supplier directly for updated address, emergency phone, and technical details.
Product Code: Refer to label or packaging for batch and code details.

Hazard Identification

GHS Classification: Irritant to eyes and skin
Signal Word: Warning
Hazard Statements: Causes mild skin irritation; causes serious eye irritation; may cause respiratory tract irritation if inhaled as dust
Pictograms: Exclamation mark symbol
Precautionary Statements: Avoid breathing dust; wear protective gloves and eye protection; wash hands thoroughly after handling; if in eyes, rinse cautiously with water.

Composition / Information on Ingredients

Chemical Name: Ellagic Acid
Synonyms: Benzoaric acid, Ellagic Tannin, 2,3,7,8-Tetrahydroxy-chromeno[5,4,3-cde]chromene-5,10-dione
Concentration: 98-100% pure
Impurities: May contain trace amounts of tannins or other plant-derived compounds.

First Aid Measures

Inhalation: Remove individual to fresh air; seek medical guidance if symptoms develop; monitor for breathing difficulties
Skin Contact: Wash with soap and plenty of water; remove contaminated clothing; seek medical advice if irritation persists
Eye Contact: Rinse cautiously with water for at least 15 minutes; remove contact lenses if present and easy to do; obtain medical attention if irritation occurs
Ingestion: Rinse mouth; seek immediate medical help if large quantities are ingested or if feeling unwell
Symptoms of Exposure: Irritation to mucous membranes, reddening or rashes on skin, watery eyes, coughing or sneezing in poorly ventilated areas.

Fire-Fighting Measures

Suitable Extinguishing Media: Use water spray, foam, dry chemical, or carbon dioxide
Unsuitable Extinguishing Media: Avoid high-pressure water jets which may spread powder
Specific Hazards: May produce carbon monoxide, carbon dioxide, or acrid smoke on combustion
Protective Equipment for Firefighters: Use self-contained breathing apparatus and suitable protective gear
Special Procedures: Evacuate area, cool fire-exposed containers with water, control runoff from fire-fighting measures.

Accidental Release Measures

Personal Precautions: Use appropriate personal protective equipment including dust mask, gloves, goggles
Environmental Precautions: Prevent discharge into drains, surface or groundwater
Spill Response: Sweep up spilled material, avoid generating dusty conditions, place in labelled container for disposal, ventilate the area, avoid exposure to incompatible substances
Decontamination Procedures: Clean surfaces with water, discard cleaning materials appropriately.

Handling and Storage

Handling: Handle in a well-ventilated place, minimize dust generation, keep away from sources of ignition, do not eat, drink, or smoke during handling, wash hands after use
Storage: Store in tightly closed container in a cool, dry, and well-ventilated location, protect from moisture, heat, and direct sunlight, keep away from strong acids or oxidizers.

Exposure Controls and Personal Protection

Occupational Exposure Limits: No established permissible exposure limit for ellagic acid
Engineering Controls: Use local exhaust or general ventilation
Personal Protection: Wear chemical-resistant gloves, safety goggles, lab coat, dust mask or respirator as needed in dusty conditions
Hygiene Measures: Wash hands, arms, and face thoroughly after handling, remove contaminated clothing, ensure eyewash stations and safety showers are accessible in work area.

Physical and Chemical Properties

Appearance: Light tan to off-white powder
Odor: Odorless
pH: Slightly acidic when dissolved in water
Melting Point: 350°C (decomposes)
Boiling Point: Decomposes before boiling
Solubility: Poorly soluble in water, solubility increases in ethanol and acetone
Flash Point: Data not available; not considered flammable
Density: About 1.7–1.8 g/cm3
Vapor Pressure: Negligible at room temperature
Partition Coefficient (log Kow): 1.1 (estimated)

Stability and Reactivity

Chemical Stability: Stable under standard handling and storage conditions
Reactivity: Incompatible with strong oxidizing agents or strong acids
Decomposition Products: Carbon monoxide, carbon dioxide, possible fumes when exposed to open flame or high temperatures
Conditions to Avoid: Prolonged exposure to heat, moisture, direct sunlight; avoid dust formation.

Toxicological Information

Acute Toxicity: Low oral and dermal toxicity in animal studies; irritation to skin and eyes possible
Chronic Effects: Repeated inhalation of dust may cause respiratory irritation
Sensitization: Not reported to be a skin sensitizer in available studies
Mutagenicity/Carcinogenicity: Current studies indicate ellagic acid does not promote tumor growth; considered non-carcinogenic to humans at dietary levels
Other Effects: Large doses over time may affect liver or kidneys in animal models, though human data are limited.

Ecological Information

Ecotoxicity: No data on aquatic toxicity; low hazard expected based on structure and use levels
Persistence and Degradability: Readily degraded by natural environmental processes, breaks down in soil and water
Bioaccumulative Potential: Not expected to bioaccumulate due to low solubility and widespread degradation
Mobility in Soil: Poorly mobile, likely to bind to soil particles
Other Adverse Effects: No evidence of toxicity to wildlife or plant species at typical environmental concentrations.

Disposal Considerations

Waste Disposal Methods: Place material and contaminated packaging in a sealed container and send for proper chemical disposal in accordance with local, state, and federal laws
Waste Classification: Not classified as hazardous waste under US EPA guidelines
Precautions: Do not release into sewers or natural watercourses, avoid landfill if alternatives exist
Special Precautions for Landfill/Incineration: Contact approved waste disposal contractors for safe handling.

Transport Information

UN Number: Not regulated as a dangerous good
Shipping Name: Ellagic Acid or chemical as labeled
Transport Hazard Class: Not assigned
Packing Group: Not assigned
Environmental Hazards: Not classed as marine pollutant
Special Precautions for Transport: Protect from physical damage, moisture, and excessive heat during transit.

Regulatory Information

Inventory Status: Listed in US TSCA, EU REACH, Canadian DSL, Australian AICS
Labeling Requirements: Must show product identification, safety, and risk phrases according to region
SARA Title III (USA): Not subject to reporting
California Prop 65: Not listed as a known carcinogen
Workplace Regulations: Employers must provide personal protective equipment, inform workers and train them on safe use
Other Regulations: Check any regional or local restrictions for food, supplement, or cosmetic uses.