Product Name: Azelaic Acid
Chemical Name: Nonanedioic acid
CAS Number: 123-99-9
Relevant Uses: Skin treatments for acne and rosacea, polymer and plastic production, lubricant ingredient
Manufacturer Contact: Check container or supplier label for details
Emergency Contacts: National Poison Control Center, Emergency Medical Services (varies by region)
Classification: Skin irritant, Eye irritant
Signal Word: Warning
Hazard Statements: Causes skin irritation, may cause eye irritation, prolonged inhalation of dust can cause respiratory tract irritation
Pictograms: Exclamation mark
Precautionary Statements: Wash hands thoroughly after handling, use in well-ventilated area, wear suitable PPE, avoid generating dust
Other Hazards: Not considered a carcinogen by NTP, IARC, or OSHA
Chemical Name: Azelaic Acid
Synonyms: 1,7-Heptanedicarboxylic acid, Nonanedioic acid
Concentration: 98–100% (pure solid)
Impurities: Minor organic acids possible, varies by batch
Eye Contact: Rinse gently with water for 15 minutes, seek medical advice if irritation persists
Skin Contact: Wash with soap and plenty of water, remove contaminated clothing and wash before reuse
Inhalation: Move to fresh air, support breathing if needed, consult a physician if symptoms continue
Ingestion: Rinse mouth with water, do not induce vomiting, consult physician or poison control for guidance
Most Important Symptoms: Irritation, redness, itching
Suitable Extinguishing Media: Dry chemical, CO2, water spray, foam
Unsuitable Methods: Direct water jet on large powder piles
Special Hazards: Emits irritating or toxic fumes under fire conditions
Protective Equipment: Self-contained breathing apparatus, full protective suit
Advice for Firefighters: Avoid inhalation of fumes, keep containers cool with water spray
Personal Precautions: Wear PPE (goggles, gloves, dust mask)
Environmental Precautions: Prevent large spills from entering drains or watercourses
Cleaning Methods: Sweep up into containers for disposal, wash spill site after material cleanup
Emergency Procedures: Restrict access to area, ventilate space, avoid raising dust
Handling: Avoid skin, eye, and respiratory contact; practice good hygiene; avoid dust formation
Storage Conditions: Store in tightly closed containers in a dry, ventilated area, away from incompatible substances like strong oxidizers
Storage Temperature: Room temperature recommended
Special Handling Instructions: Use spark-proof tools in bulk scenarios, minimize direct contact
Exposure Limits: No specific ACGIH or OSHA exposure limit defined
Engineering Controls: Local exhaust ventilation, general ventilation
Personal Protection: Protective gloves (nitrile or latex), safety goggles, lab coat
Respiratory Protection: NIOSH-approved dust mask for powder use
Hygiene Measures: Wash hands after handling, do not eat, drink, or smoke during handling
Appearance: White crystalline powder
Odor: Odorless to faint
pH: Slightly acidic (1% solution: pH 4–5.5)
Melting Point: 105–106°C
Boiling Point: Decomposes
Flash Point: >200°C
Solubility: Soluble in hot water, sparingly soluble in cold water and alcohol
Vapor Pressure: Negligible
Bulk Density: About 1.46 g/cm³
Chemical Stability: Stable under recommended storage conditions
Reactivity: No hazardous reactivity with common substances
Conditions to Avoid: Excessive dust generation, prolonged exposure to humidity
Incompatible Materials: Strong oxidizing agents, strong acids
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, acrid smoke (on combustion)
Routes of Exposure: Eye, skin, inhalation, ingestion
Acute Toxicity: Oral LD50 (rat) > 5000 mg/kg
Skin Irritation: May cause moderate irritation
Eye Irritation: May cause redness, tearing
Chronic Effects: No evidence of carcinogenicity or reproductive toxicity reported
Other Effects: Prolonged or repeated skin contact can cause dryness
Ecotoxicity: Low aquatic toxicity in available studies
Persistence & Degradability: Readily biodegradable in soil and water
Bioaccumulative Potential: Not expected to bioaccumulate
Mobility in Soil: Moderate mobility, depending on local conditions
Other Adverse Effects: No data indicating significant environmental risk when used responsibly
Waste Treatment Methods: Incinerate under controlled conditions or dispose via licensed waste contractor
Special Precautions: Do not release large quantities into watercourses
Empty Container Handling: Rinse thoroughly before disposal or recycling
Disposal Regulations: Follow local, regional, national, and international guidelines for non-hazardous organic chemicals
UN Number: Not classified as hazardous for transport
Transport Hazard Class: Not regulated
Packing Group: Not regulated
Marine Pollutant: Not a marine pollutant
Special Precautions: Secure packaging to prevent physical damage, avoid moisture during transport
US TSCA Inventory: Listed
EU REACH Registration: Registered
GHS Labeling: Applies—skin and eye irritant
Other Regulations: No specific SARA, CERCLA, or CAA restrictions; meet all workplace and environmental safety regulations by jurisdiction
Workplace Labelling: Include pictogram, signal word, hazard statements on containers used at point of work
