Product Name: 1,2,3-Trimethoxybenzene
Chemical Formula: C9H12O3
Synonyms: Benzene, 1,2,3-trimethoxy-, Trimethoxybenzene
CAS Number: 697-23-4
Recommended Use: Laboratory research, chemical synthesis
Supplier Identification: Chemical manufacturers or specialized lab supply houses
Emergency Contact: Refer to supplier’s information or local emergency line
Hazard Classification: Not classified as a hazardous substance under GHS; lacks acute toxicity, but skin and eye irritation possible
Label Elements: No pictogram required under current classification
Signal Word: Not applicable
Hazard Statements: May cause mild skin or eye irritation upon contact
Precautionary Statements: Use protective gloves and eye wear; avoid inhalation of vapors or dust; use only with adequate ventilation; do not ingest
Potential Health Effects: Eye and skin contact may provoke redness or discomfort; inhalation may irritate respiratory passages; excessive exposure may cause headaches or dizziness
Environmental Hazards: Not expected to pose serious hazard at small scale but large releases could affect aquatic environments
Chemical Name: 1,2,3-Trimethoxybenzene
Concentration: Above 99%
Impurities: Trace organic compounds possible, details provided by supplier as part of certificate of analysis
Other Components: None included intentionally
Eye Contact: Rinse gently with plenty of water for several minutes; remove contact lenses if present; continue rinsing, seek medical help for continued irritation
Skin Contact: Wash thoroughly with soap and water; remove contaminated clothing; seek attention for persistent symptoms
Inhalation: Move person to fresh air; keep at rest and warm; medical support if symptoms develop or persist
Ingestion: Rinse mouth with water; do not induce vomiting; seek immediate medical attention for large quantities
Notes for Medical Personnel: Treat symptoms; no specific antidote known
Suitable Extinguishing Media: Water spray, dry chemical, CO2, foam
Unsuitable Media: Avoid direct water jets, which may scatter product
Specific Hazards: Combustion forms carbon oxides and irritating fumes
Special Protective Equipment for Firefighters: Use full protective gear and self-contained breathing apparatus
Firefighting Procedures: Cool containers with water, control run-off, keep away from ignition sources
Personal Precautions: Equip with gloves and safety glasses; ventilate area well; avoid breathing dust
Environmental Precautions: Prevent release to soil, watercourses, or drains
Clean-Up Methods: Absorb spills with inert material like sand or earth, transfer to containers for disposal; clean area with soap and water
Handling: Practice good laboratory hygiene; work under fume hood for large quantities; avoid skin and eye contact
Storage: Store in tightly closed containers; keep in cool, dry, well-ventilated area; avoid strong light and moisture; keep away from oxidizing agents
Incompatibility: Avoid storage with strong acids, bases, and oxidizers
Occupational Exposure Limits: No specific country limits established; minimize exposure as a precaution
Engineering Controls: Use ventilation, preferably chemical fume hood, especially with solids
Personal Protective Equipment: Chemical-resistant gloves, safety goggles, lab coats; in case of dust, use respirator (N95 or equivalent); prohibit eating, drinking, or smoking during use
Hygiene Measures: Wash hands thoroughly, launder contaminated clothing before reuse
Appearance: White to off-white crystalline powder
Odor: Faint aromatic
Melting Point: 53–56°C
Boiling Point: 262°C
Vapor Pressure: Low at room temperature
Solubility: Soluble in organic solvents; limited water solubility
Density: Approximately 1.17 g/cm³
Flash Point: >110°C (closed cup)
Viscosity: Not available for solid material
Partition Coefficient (log Kow): Estimated 1.6–2.5
Chemical Stability: Stable under normal storage conditions
Reactivity: No hazardous reactions in normal use
Conditions to Avoid: High heat, open flames, excessive moisture
Incompatible Materials: Strong oxidizers, strong acids, strong bases
Hazardous Decomposition Products: Produces carbon monoxide, carbon dioxide under fire or excessive heating
Acute Toxicity: Data limited, estimated low toxicity
Irritation: Mild eye and skin irritant potential
Respiratory Effects: Can cause coughing, soreness or discomfort if significant inhalation occurs
Sensitization: Not known to cause allergic reactions
Chronic Effects: No evidence of carcinogenic, mutagenic, or reproductive effects in available studies
Routes of Exposure: Skin, eyes, inhalation, ingestion
LD50 (oral, rat): >2000 mg/kg (estimated)
Aquatic Toxicity: Not highly toxic to aquatic life in small quantities; limited persistence expected
Mobility: Moderately mobile in soil; low volatility from water or soil surface
Persistence and Degradability: Expected to degrade by microbial action
Bioaccumulation: Potential for low bioaccumulation based on log Kow
Other Adverse Effects: Large spills to waterways could disrupt aquatic organisms temporarily
Waste Handling: Collect and place in suitable labeled waste container
Disposal Methods: Dispose of as hazardous chemical waste through permitted facility; comply with local and national regulations
Packaging: Dispose of contaminated packaging according to regulations, rinse thoroughly if possible
Avoid Release: Do not pour into drains, water bodies, or the environment
UN Number: Not regulated for transport
Proper Shipping Name: Not classified as hazardous
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Environmental Hazards: None for road, sea, or air transport at small scale
Special Precautions: Basic packaging, avoid moisture and rough handling; secure upright during transport
TSCA Inventory Status: Listed
REACH Registration: Exempt for research and development, bulk use requires registration
OSHA Status: Not regulated as hazardous chemical
EPA Status: Not listed as hazardous
SARA Title III: Not subject to reporting requirements
WHMIS Classification (Canada): Not classified as controlled product
Other Regulations: Review local, state, and federal rules before disposal, handling, or larger use situations
